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        Alternatives N/A Perineuronal net degradation rescues CA2 plasticity in a mouse model of Rett syndrome Kelly E. Carstens, … , Georgia M. Alexander, Serena M. Dudek Kelly E. Carstens, … , Georgia M. Alexander, Serena M. Dudek Published July 6, 2021 Citation Information: J Clin Invest. 2021;131(16):e137221. https://doi.org/10.1172/JCI137221. View: Text | PDF Perineuronal net degradation rescues CA2 plasticity in a mouse model of Rett syndrome Text PDF Abstract Perineuronal nets (PNNs), a specialized form of extracellular matrix, are abnormal in the brains of people with Rett syndrome (RTT). We previously reported that PNNs function to restrict synaptic plasticity in hippocampal area CA2,...

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